Topics - Cyclodextrin

Cyclodextrinis a cyclic polymer of alpha-D-glucopyranose. The common cyclodextrins used in chromatography are the alpha-, beta- and gamma-cyclodextrins which have been shown to contain 6 (cyclohexamylose), 7 (cycloheptamylose) and 8 (cyclooctamylose) glucose units, respectively. These cyclic, chiral, torus shaped macromolecules contain the D(+)-glucose residues bonded through a-(1- 4)glycosidic linkages. They are among the most popular phases for doing chiral separations in HPLC.