Topics - Chloroheptane

Chloroheptane The chlorinated hydrocarbons are very strongly dispersive (hydrophobic) solvents and are used in liquid chromatography (LC) when the normal hydrocarbons are insufficiently dispersive to elute the solutes in a reasonable time. Chloroheptane is a popular halogenated solvent for this purpose as its boiling point makes it practical for LC, its is readily available, relatively inexpensive and has a strong dispersive character. It is often used mixed with n-heptane and gradient elution is sometimes carried out from 100% n-heptane to 100% chloroheptane. Chloroheptane is also used mixed with an appropriate ester as a mobile phase that provides a combination of strong dispersive interactions and relatively weak polar interactions.