The Thermodynamics of Chromatography - The Distribution of Standard Energy Between Different Types of Molecular Interactions > The Concept of Complex Formation > Page 48



The Concept of Complex Formation

In an attempt to explain the nature of polar interactions, Martire et al. (11) developed a theory assuming that such interactions could be explained by the formation of a complex between the solute and the stationary phase with its own equilibrium constant. Matire and Riedl adopted a procedure used by Langer et al. (12) and divided the solute activity coefficient into two components.


               where () is the specific retention volume of the solute,

                         () is the fully corrected solute activity


                        ()  is the solute bulk vapor pressure,

                     ()  is  the stationary phase molecular weight,

                         (R)  is the gas constant,

                    and (c)  is the fraction of the solute that is complexed.