Principles and Practice of Chromatography - Peak Dispersion in a Chromatographic Column > The Resistance to Mass Transfer in the Stationary Phase > Page 47

 

Figure 23 Resistance to Mass Transfer in the Stationary Phase

 

All four molecules will continue moving down he column, while molecules 5 and 6 diffuse to the interface. By the time molecules 5 and 6 enter the mobile phase, the other four molecules will have been smeared along the column and the original 6 molecules will be dispersed.

 

Van Deemter derived an expression for the variance from the resistance to mass transfer in the stationary phase, (), which is as follows:

 

(7)