Preparative Chromatography - Packing Preparative Columns > Axial Compression > Page 37

This technique will automatically take up bed volume changes (provided they do not exceed the limits of flexibility of the cartridge) and can automatically compensate for the bed reorganization during operation. The radial compression technique is generally applied in columns of up to 20 cm (8 in.) in diameter.

Axial Compression

The alternative technique for bed stabilization by compression is to use an axial rather than a radial force.


Figure 18 Longitudinal Compression for Preparative Column Bed Stabilization