Gas Chromatography Detectors - Detector Linearity > Determination of Response Index > The Logarithmic Dilution Method of Linearity Measurement > Page 9

 

The mass of solute removed (dm) is given by

 

where (Ct) is the concentration of solute in the vessel after time (t).

The mass change (dm) will result in a change in concentration (dCt)

and

Integrating

where (Q) is the flow rate,
(v) is the volume flow of mobile phase through the system after time (t)
and (k) is the integration constant.